Researcher in Statistical Genetics

INRAE, GenPhySE Lab

Biography

I am a researcher in statistical genetics at the GenPhySE INRAE Lab. My research interests include population genetics, quantitative genetics and genomics. My group develops new methods for the analysis of large scale genetic data with a particular interest in understanding the evolution of livestock species.

Interests
  • Statistics
  • Genetics
  • Evolution
  • Python programming language
Education

  • PhD in Genetics, 2003

    Université Paris-Sud

  • MSc in Agronomy and Plant Breeding, 2000

    AgroParisTech

Experience

 
 
 
 
 
Senior Researcher
INRAE, Animal Genetics
Jan 2021 – Present Toulouse, France

Leader of the Dynagen Research group

  • Modelling
  • Analysis of large scale genetic data
  • Software development
 
 
 
 
 
Research Associate
INRA, Animal Genetics
Sep 2006 – Dec 2020 Toulouse, France
 
 
 
 
 
Post-doctoral Fellow
University of Washington, Department of Statistics, Matthew Stephens Lab
Feb 2004 – Aug 2006 Seattle, WA, USA
Developped statistical methods for genome-wide association studies based on genotype imputation

Projects

Evolution of recombination
What are the genetic determinisms of recombination ? How does it evolve ?
Evolution of recombination
Genetics of honeybee populations
Understand the genetic structure and diversity of honeybee populations
Population Genomics
Using genomic data to understand the evolutionary history of populations

Preprints

Sequence-based genome-wide association studies reveal the polygenic architecture of Varroa destructor resistance in Western honey bees Apis mellifera
Honey bees, Apis mellifera, have experienced the full impacts of globalisation, including the recent invasion by the parasite Varroa …
Sonia E. Eynard, Fanny Mondet, Benjamin Basso, Olivier Bouchez, Tabatha Bulach, Yves Le Conte, Benjamin Dainat, Axel Decourtye, Lucie Genestout, Matthieu Guichard, François Guillaume, Emmanuelle Labarthe, Barbara Locke, Rachid Mahla, Joachim de Miranda, Markus Neuditschko, Florence Phocas, Yannick Poquet, Christina Sann, Rémi-Félix Serre, Kamila Tabet, Alain Vignal, Bertrand Servin
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The Black Honey Bee Genome: Insights on Specific Structural Elements and a First Step towards Pan-Genomes
Background The actual honey bee reference genome, HAv3.1, was produced from a commercial line sample, thought to have a largely …
Sonia E Eynard, Christophe Klopp, Kamila Canale-Tabet, William Marande, Celine Vandecasteele, Celine Lopez-Roques, Quentin Boone, Cecile Donnadieu, Bertrand Servin, Alain Vignal
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Recent Publications

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Sonia E. Eynard, Fanny Mondet, Benjamin Basso, Olivier Bouchez, Tabatha Bulach, Yves Le Conte, Benjamin Dainat, Axel Decourtye, Lucie Genestout, Matthieu Guichard, François Guillaume, Emmanuelle Labarthe, Barbara Locke, Rachid Mahla, Joachim de Miranda, Markus Neuditschko, Florence Phocas, Yannick Poquet, Christina Sann, Rémi-Félix Serre, Kamila Tabet, Alain Vignal, Bertrand Servin (2024). Sequence-based genome-wide association studies reveal the polygenic architecture of Varroa destructor resistance in Western honey bees Apis mellifera. bioRxiv.

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Arianna Manunza, Johanna Ramirez-Diaz, Paolo Cozzi, Barbara Lazzari, Gwenola Tosser-Klopp, Bertrand Servin, Anna M. Johansson, Lise Grøva, Peer Berg, Dag Inge Våge, Alessandra Stella (2023). Genetic Diversity and Historical Demography of Underutilised Goat Breeds in North-Western Europe. Nature Publishing Group.

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Alice Danguy des Déserts, Nicolas Durand, Bertrand Servin, Ellen Goudemand-Dugué, Jean-Marc Alliot, Daniel Ruiz, Gilles Charmet, Jean-Michel Elsen, Sophie Bouchet (2023). Comparison of Genomic-Enabled Cross Selection Criteria for the Improvement of Inbred Line Breeding Populations.

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Sonia E Eynard, Christophe Klopp, Kamila Canale-Tabet, William Marande, Celine Vandecasteele, Celine Lopez-Roques, Quentin Boone, Cecile Donnadieu, Bertrand Servin, Alain Vignal (2023). The Black Honey Bee Genome: Insights on Specific Structural Elements and a First Step towards Pan-Genomes. Cold Spring Harbor Laboratory.

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M. Guichard, B. Dainat, S. Eynard, A. Vignal, B. Servin, M. Neuditschko (2022). Identification of Quantitative Trait Loci Associated with Calmness and Gentleness in Honey Bees Using Whole-Genome Sequences.

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Popular Topics

Abscam alleles animals Apis mellifera breeding chromosome mapping female genetic genome genotype haplotypes male polymorphism population genetics selection sequence analysis sheep single nucleotide Sus scrofa transcriptome

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